Functional Nucleic Acids for Analytical Applications by Yingfu Li (English) Pape

Description: Functional Nucleic Acids for Analytical Applications by Yingfu Li, Yi Lu The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description Nature has long used nucleic acid aptamers and enzymes for regulatory activities, such as the recently discovered "riboswitches" involved in gene expression. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems. Notes This is the first book in the rapidly emerging field of analytical applications for nucleic acids. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm. It has opened up new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems. Back Cover Both DNA and RNA can serve purposes beyond simple genetic storage and transfer e" for example, they can also be employed as enzymes (for catalysis) and receptors (for ligand binding). Increasingly, researchers are making interesting use of these molecules, now collectively called functional nucleic acids. This book, containing chapters written by leading experts in relevant fields, provides timely accounts of diverse analytical applications that take advantage of the functional nucleic acids. The book is written for academic, clinical and industrial scientists and graduate students who may consider exploring functional nucleic acids in their research or practice. Table of Contents Overview of Functional Nucleic Acids and Their Analytical Applications.- Introductory Remarks.- Natural Functional Nucleic Acids: Ribozymes and Riboswitches.- Artificial Functional Nucleic Acids: Aptamers, Ribozymes, and Deoxyribozymes Identified by In Vitro Selection.- Functional Nucleic Acid Sensors Based on Different Transduction Principles.- Fluorescent Aptamer Sensors.- Fluorescent Ribozyme and Deoxyribozyme Sensors.- Colorimetric and Fluorescent Biosensors Based on Directed Assembly of Nanomaterials with Functional DNA.- Electrochemical Approaches to Aptamer-Based Sensing.- Amplified DNA Biosensors.- Other Emerging Analytical Applications.- Aptamers in Affinity Separations:Capillary Electrophoresis.- Aptamers in Affinity Separations: Stationary Separation.- Aptamer Microarrays.- The Use of Functional Nucleic Acids in Solid-Phase Fluorimetric Assays.- Functional Nucleic Acid Sensors as Screening Tools.- Nucleic Acids for Computation.- DNAzymes in DNA Nanomachines and DNA Analysis. Review From the reviews: "This book consists of 15 chapters contributed by experts in the field of functional nucleic acids, mostly in the area of specific analytical applications of nucleic acids ... . this book affords a comprehensive collection of clearly presented, up-to-date reviews that broadly cover the numerous applications of functional nucleic acids. ... The chapters are of high quality ... that will be useful to newcomers entering the field of functional nucleic acids and to those interested in exploring other applications complementary to their own niches." (Jennifer S. Brodbelt, Journal of the American Chemical Society, Vol. 131 (32), 2009) "The book is well structured and combines 15 insightful reviews written by many leading experts. ... Functional Nucleic Acids for Analytical Applications is a comprehensive and well written book. With its excellent review of recent progress and critical outlook of future directions it will be very valuable for researchers wishing to explore the unique properties of FNAs for different applications in analytical and bioanalytical chemistry." (Xiaohong Fang, Analytical and Bioanalytical Chemistry, Vol. 398, June, 2010) Long Description Nature has long used nucleic acid aptamers and enzymes for regulatory activities, such as the recently discovered "riboswitches" involved in gene expression. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems. Review Quote From the reviews:"This book consists of 15 chapters contributed by experts in the field of functional nucleic acids, mostly in the area of specific analytical applications of nucleic acids … . this book affords a comprehensive collection of clearly presented, up-to-date reviews that broadly cover the numerous applications of functional nucleic acids. … The chapters are of high quality … that will be useful to newcomers entering the field of functional nucleic acids and to those interested in exploring other applications complementary to their own niches." (Jennifer S. Brodbelt, Journal of the American Chemical Society, Vol. 131 (32), 2009)The book is well structured and combines 15 insightful reviews written by many leading experts. … Functional Nucleic Acids for Analytical Applications is a comprehensive and well written book. With its excellent review of recent progress and critical outlook of future directions it will be very valuable for researchers wishing to explore the unique properties of FNAs for different applications in analytical and bioanalytical chemistry. (Xiaohong Fang, Analytical and Bioanalytical Chemistry, Vol. 398, June, 2010) Feature First in the rapidly emerging field on analytical applications for nucleic acids With interdisciplinary approach, a valuable tool for researchers in chemistry, biology, and engineering One of the first books in the series Integrated Microanalytical Systems, recently renamed Integrated Analytical Systems, edited by R. Potyrailo Description for Sales People This is the first book in the rapidly emerging field of analytical applications for nucleic acids. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm. It has opened up new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems. Details ISBN1441925309 Publisher Springer-Verlag New York Inc. Series Integrated Analytical Systems Year 2010 Edition 1st ISBN-10 1441925309 ISBN-13 9781441925305 Format Paperback Imprint Springer-Verlag New York Inc. Place of Publication New York, NY Country of Publication United States Edited by Yi Lu Short Title FUNCTIONAL NUCLEIC ACIDS FOR A Language English Media Book DEWEY 572.8 Pages 396 Illustrations VIII, 396 p. Publication Date 2010-11-19 AU Release Date 2010-11-19 NZ Release Date 2010-11-19 US Release Date 2010-11-19 UK Release Date 2010-11-19 Author Yi Lu Edition Description Softcover reprint of hardcover 1st ed. 2009 Alternative 9780387737102 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96236597;

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